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J. (1969), Gut, 10, 575. Asherson, G. L. (1967), Brit. med. , 2, 479. Aubrey, D . A. (1970), Arch. Surç. {Chicago), 100, 144. Bell, H. G. (1934), Calif. West. , 41, 239. , Weeke, B. and Yssing, M. (1968), Scand. J. , 3, 481. Bendixen, G. (1969), Gut, 10, 631. Bianco, G. (1966), Ann. Ital. , 42, 1118. , Spiro, H. and Thayer, W. (1966), Amer. J. Digest. , 11, 572. Bockus, H. L. and Lee, W. E. (1935), Ann. , 102, 412. Bockus, H. L. (1945), / . Amer. med. , 127, 449. Brobergerer, O. and Perlmann, P.

Barbezat, G. O. and Raynham, B. (1968), S. Afr. med. , 42, 1099. Chacon, A. C. E. (1966), Rev. , 5, 221. Colcock, B. P. and Vansant, J. H. (1960), Lahey Clin. , 12, 53. Crohn, B. B. and Yarnis, H. (1958), Regional Ileitis, 2nd edition. New York: Grune and Stratton. Cumming-Smith, C. (1970), Personal communication. Daffner, J. E. and Brown, C. H. (1958), Ann. Int. , 49, 580. De Beaux, J. (1970), Personal communication. De Dombal, F . T. (1970), Proc. Roy. Soc. , in press. Edwards, H. C. (1964), / .

Five had Crohn's disease and 30 had acute appendicitis; this is a ratio of 1 : 6 although acute appendicitis 36 Crohn's Disease is several hundred times more common than any acute presentation of Crohn's disease. Schmidt et al. (1968) have given a useful description of how to differentiate between Crohn's disease and diverticulitis of the colon. Both diseases may present in the older age groups, and they may coexist. The possibility that mural damage caused by diverticulitis initiates a sequence of events that finally manifests itself as colonie Crohn's disease has not been eliminated.

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